And even with gun builds, only a small handful of guns do any significant damage to Mayhem 10 enemies, and only if they drop with 100-300% damage anointments on them. This has utterly destroyed all kinds of builds, namely anything using action skills like a Moze Iron Bear build or anything that doesn’t use guns like an Amara melee build.
The main problem is scaling in the new Mayhem system, where by the time you get up to Mayhem 10, enemies have 12,500% health.